Center for advanced chronic diseases ACCDiS
He invites them to his seminar cycle of diseases cardiovascular-2018


Dr. Ramón Corbalán
Cardiovascular Division
School of medicine, Pontificia Universidad Católica de Chile
Research Center for advanced diseases Chronicles-ACCDiS

02 AUGUST 2018
09:00 HR.

1st floor, Sector A
Hospital Clínico, U de Chile
Santos Dumont #999


Atrial fibrillation is the most common sustained arrhythmia and fundamentally affects the population over 65 years. Clinical conditions predisposing: high blood pressure, heart failure, diabetes mellitus and chronic renal failure. Are the risks associated with atrial fibrillation: cerebral embolism, heart failure and sudden death. The introduction of new direct oral anticoagulant drugs has helped reduce the incidence of cerebral embolism. At the same time, the identification of risk factors that predispose to heart failure has also helped reduce mortality from this cause. However, a problem not yet solved is the most appropriate treatment of patients with atrial fibrillation and renal failure.

Our working group has researched for several years factors predisposing to the development of atrial fibrillation, paroxysmal or permanent type. For these purposes, we have investigated the left atrial function and biomarkers that are associated with the development of atrial fibrillation. They include early left atrial contractile dysfunction, assessed by echocardiography with speckle tracking, and measurement of soluble adhesion molecules (VCAM and sVCAM-1). Both are independent of the development of atrial fibrillation risk factors and will be discussed in this presentation.