The article published inBiomaterials Science, presents an innovative nanosystem based on gold nanobars that helps diagnose and treat Alzheimer's.

Recently the research was selected by the Royal Society of Chemistry, Renowned scientific society in the United Kingdom, to be included in the collection "Celebrating Latin American chemistry”, a virtual forum through which the community of Latin American chemists located anywhere in the world can share and discuss the results and advances of their research.

Dr. Marcelo Kogan, professor at the University of Chile and principal investigator of the Advanced Center for Chronic Diseases (ACCDIS), together with his research team, worked on the detection and reduction of amyloid load by in vivo computed microtomography, through the use of multifunctionalized gold nanobars.

"In the studio, We use gold particles coated with two types of molecules (GNRs-D1/Ang2). One of them allows the blood-brain protective barrier to be crossed and the brain accessed, while the other, Decreases amyloid plaques, plaques responsible for neuronal damage in diseases such as Alzheimer's," explained Dr. Macelo Kogan, he also stressed that this scientific advance, It has great potential as a tool for detecting neural factors of the disease.

Because gold can be seen through X-rays, We can locate the plaques that form from this protein, Preventing neurodegeneration, Reported.

Although the study is in the preclinical phase, The results showed a noticeable decrease in amyloid plaques and brain inflammation, giving the go-ahead to consider them as preventive studies not only for Alzheimer's, but also of more neurodegenerative diseases, opening the door to more effective processes, less invasive and that could be applied in the near future.

See post here: https://www.accdis.cl/wp-content/uploads/2024/11/morales-zavala2021.pdf